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In 1993 Jacobs Duffy Designs Inc. created its own design and licensing company, Marc Jacobs International Company, L.P., thereafter relaunching Jacobs’s signature brand, which debuted a line of menswear the following year. In 1997 Jacobs opened the first of his numerous boutiques and—in exchange for the financial support of his fashion house—signed on as creative director for Louis Vuitton, where he revitalized the brand, designing its first line of ready-to-wear clothing and expanding its accessories line. In the early 21st century Jacobs globally expanded his signature brand and launched a more affordable line of sportswear, Marc by Marc Jacobs (2001). He also collaborated with others, including designer Stephen Sprouse, with whom he launched the immediately successful Louis Vuitton Speedy graffiti handbag (2001), which looked as if it had been spray-painted with the company’s name. In 2003 he worked with the Japanese visual artist Takashi Murakami to produce the critically acclaimed Louis Vuitton Eye Love Monogram collection, which replaced the brand’s traditional beige-and-brown monogrammed canvas with a multicoloured palette featuring pop-art graphics, such as cartoon eyes. In 2005 Jacobs launched a line of children’s wear, Little Marc Jacobs. How to use suggest spritz onto pulse points.