Cambridge Texts In Biomedical Engineering: The Cell As A Machine Hardcover

Michael Sheetz

This unique introductory text explains cell functions using the engineering principles of robust devices. Adopting a process-based approach to understanding cell and tissue biology, it describes the molecular and mechanical features that enable the cell to be robust in operating its various components, and explores the ways in which molecular modules respond to environmental signals to execute complex functions. The design and operation of a variety of complex functions are covered, including engineering lipid bilayers to provide fluid boundaries and mechanical controls, adjusting cell shape and forces with dynamic filament networks, and DNA packaging for information retrieval and propagation. Numerous problems, case studies and application examples help readers connect theory with practice, and solutions for instructors and videos of lectures accompany the book online. Assuming only basic mathematical knowledge, this is an invaluable resource for graduate and senior undergraduate students taking single-semester courses in cell mechanics, biophysics and cell biology.

1107052734

English

CAMBRIDGE UNIVERSITY PRESS

26 March 2019

434

Michael Sheetz is the Founding Director of the Mechanobiology Institute and a Distinguished Professor in the Department of Biological Sciences at the National University of Singapore. Hanry Yu is a Professor in both the Department of Physiology and the Mechanobiology Institute at the National University of Singapore. He is also the Director of the National University Health System's research facilities in microscopy and cytometry.