Phytochemicals As Lead Compounds For New Drug Discovery Paperback

Chukwuebuka Egbuna

Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This book presents fundament concepts and factors affecting the choice for plant-based products, as well as recent advances in computer-aided drug discovery and FDA drug candidacy acceptance criteria. It also details the various bioactive lead compounds and molecular targets for a range of life-threatening diseases including cancer, diabetes, and neurodegenerative diseases. Written by a global team of experts, Phytochemicals as Lead Compounds for New Drug Discovery is an ideal resource for drug developers, phytochemists, plant biochemists, food and medicinal chemists, nutritionists and toxicologists, chemical ecologists, taxonomists, analytical chemists, and other researchers in those fields. It will also be very valuable to professors, students, and researchers in this domain.

0128178906

9780128178904

English

Elsevier

10-Sep-19

378

Chukwuebuka Egbuna is a chartered chemist, a chemical analyst, and an academic researcher. He is a member of the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), the Society of Quality Assurance (SQA) (USA), and the Royal Society of Chemistry (RSC) (United Kingdom). He has been engaged in a number of roles at New Divine Favor Pharmaceutical Industry Limited, Akuzor Nkpor, Anambra State, Nigeria, and Chukwuemeka Odumegwu Ojukwu University (COOU) in Nigeria. He has collaboratively worked on and published quite a number of research articles in the area of phytochemistry, nutrition, and toxicology and other related areas. Mr. Egbuna has edited a 3-volume set book of phytochemistry with Apple Academic Press (Phytochemistry, Volume 1: Fundamentals, Modern Techniques, and Applications; Phytochemistry, Volume 2: Pharmacognosy, Nanomedicine, and Contemporary Issues; and Phytochemistry, Volume 3: Marine Sources, Industrial Applications and Recent Advances). He has also co-edited another book on Phytochemistry: An in-silico and in-vitro Update with Springer Nature, Singapore. He is also working on other books with Elsevier, Springer Nature, Wiley-Blackwell, and Apple Academic Press. He is a reviewer and editorial board member of various journals, including serving as a website administrator for the Tropical Journal of Applied Natural Sciences (TJANS), a journal of the faculty of Natural Sciences, COOU. His primary research interests are in phytochemistry, nutrition and toxicology, food and medicinal chemistry, and analytical biochemistry. He obtained his BSc and MSc degrees in biochemistry at COOU and is presently a PhD fellow in Nutritional Biochemistry and Toxicology with the World Bank Africa Centre of Excellence, Centre for Public Health and Toxicological Research (PUTOR), University of Port-Harcourt, Rivers State, Nigeria.